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Molecular biology

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The steady and debilitating progression of Parkinson’s is thought to be driven by the gradual accumulation of misfolded proteins in the brain. The EU-funded SYN-CHARGE project made the surprising discovery that these problem proteins may be targeted by peptide chains made from mirror image amino acids. The work lays the foundation for potential new therapies for several neurodegenerative diseases.
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Currently there are no therapy options available for those suffering acute radiation sickness. But hope is on the horizon. A combination of carbon and pectin developed by the EU-funded NanoMed project can absorb damaging molecules generated in the body after exposure to radiation. It’s the first step towards a simple pill that can be given to those exposed to high levels of radiation.
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As Europe’s population grows older, the burden of age-related diseases is rising. A promising avenue of research is understanding how protein dysfunction can drive cancer and neurodegenerative disorders. The EU-funded PhasAGE project created a research centre focused on protein phase separation, growing Europe’s research capacity to prevent and treat age-related diseases.
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Microbiomes may have the potential to benefit the global food system, but tapping that potential requires coordinated research – which currently isn’t the case. The EU-funded MicrobiomeSupport project aims to change this by mapping the research landscape and highlighting the need to standardise data. In doing so, it is ensuring that microbiome research can support safe, healthy and sustainable food systems.
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A better understanding of microbial communities could bring profound benefits to the agri-food sector. The EU-funded MASTER project has developed a wide range of microbiome products, foods, services and processes. These innovations are helping improve the quantity, quality, safety and sustainability of our food and farms.
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The many microscopic organisms, or microbiome, that live in our gut play a big part in keeping us healthy, yet a breakdown in communication between them and the rest of the body can badly affect our health. The EU-funded META-BIOME project set out to understand the causes of this miscommunication. To understand this could allow for new treatments against many diseases, benefiting all citizens.
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When COVID-19 was declared a global pandemic by the WHO, an EU funded research project immediately stepped up to the plate. BioExcel, one of Europe's leading centres for computational biomolecular research, gave priority access to its supercomputing facilities and cutting-edge software. This will help researchers and innovators across Europe in the fight against coronavirus.
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EU-funded researchers have applied engineering know-how to understand what controls the mechanical strength of living cells. Their findings offer new insights into the spread of cancers as well as into diseases of the heart and nervous system.