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Imagine peering into the human brain and observing its activity. Or guiding a surgeon’s hand in real time as they target cancerous tissue in the body. The EU-funded 4D-PET project offers enhanced medical imaging to transform how we diagnose and treat illness.
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Sleep is one of biology’s most universal – and perplexing – phenomena. Why do animals need sleep, a state that seemingly leaves them vulnerable and unproductive? The EU-funded SleepSynapses project offered new insights to better understand sleep’s fundamental purpose.
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For many years, psychology and brain research were left underdeveloped in Romania. Now the EU-funded NEUROTWIN project has helped set up a top brain research institute in Cluj-Napoca through improved collaboration with EU neuroscience institutes. The benefits range from new medical treatments to technologies used in electrical grid maintenance and video games.
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When the systems that regulate proteins fail, the outcome can be cancer, heart disease or neurodegenerative disorders. Research by the EU-funded Nedd8Activate project offers a window into how the body clears away unwanted proteins. This knowledge could help treat protein dysregulation, and pave the way for drugs that flag disease-causing proteins for elimination.
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Metastasis is responsible for over 90 % of cancer-related deaths. Yet little focus has been placed on the elusive cells responsible for spreading the disease, which circulate through the bloodstream, making identification and analysis challenging. The EU-funded SCALPEL project set out to save lives by developing a microchip device to detect and sort metastatic cells from blood samples.
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Cancer is one of the leading causes of death in the EU. Researchers in the EU-funded Survive project examined how cells adapt to acidic conditions – a trait that can allow tumours to grow. Their findings highlight new ways to identify aggressive cancers, and point to potential new treatments to regulate acid resistance.
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The thyroid gland produces many of the body’s essential hormones, but chemicals found in food, clothes and furniture can interfere with its function. Predicting the toxicity of these chemicals – especially at low doses – has proven difficult. The EU-funded SCREENED project created a model thyroid made of human cells to provide more accurate testing, as well as reduce reliance on animal studies.
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The steady and debilitating progression of Parkinson’s is thought to be driven by the gradual accumulation of misfolded proteins in the brain. The EU-funded SYN-CHARGE project made the surprising discovery that these problem proteins may be targeted by peptide chains made from mirror image amino acids. The work lays the foundation for potential new therapies for several neurodegenerative diseases.
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Currently there are no therapy options available for those suffering acute radiation sickness. But hope is on the horizon. A combination of carbon and pectin developed by the EU-funded NanoMed project can absorb damaging molecules generated in the body after exposure to radiation. It’s the first step towards a simple pill that can be given to those exposed to high levels of radiation.
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There is an acute need for implantable devices that can report prompt and accurate data about the body’s chemistry. The EU-funded ImplantSens project developed long-term implantable biosensors for glucose monitoring, to improve the management of diabetes. The project also helped train the next generation of scientists to carry on this work.