The steady and debilitating progression of Parkinson’s is thought to be driven by the gradual accumulation of misfolded proteins in the brain. The EU-funded SYN-CHARGE project made the surprising discovery that these problem proteins may be targeted by peptide chains made from mirror image amino acids. The work lays the foundation for potential new therapies for several neurodegenerative diseases.
Mercury pollution presents a significant risk to environment and human health, in particular its accumulation in edible fish. The EU-funded Global Mercury Observation and Training network project (ITN GMOS-Train) helped model mercury’s chemical behaviour and fate in land, air and marine environments. The work will support public health initiatives and make more informed dietary choices possible.
Currently there are no therapy options available for those suffering acute radiation sickness. But hope is on the horizon. A combination of carbon and pectin developed by the EU-funded NanoMed project can absorb damaging molecules generated in the body after exposure to radiation. It’s the first step towards a simple pill that can be given to those exposed to high levels of radiation.
Ancient inscriptions can teach us a lot about past civilisations. The problem is that these inscriptions are often illegible, or their place of origin is unknown. To help, the EU-funded PythiaPlus project developed an AI-based tool that historians can use to restore missing text, and establish an inscription’s original date and place of writing.
By 2050, the global population will soar to 9 billion, with three quarters of this number living in urban areas. Pressure on ecosystems due to population growth, urbanisation and climate change will reach its peak. The EU-funded project ECORISK2050 set out to tackle the daunting task of future environmental risk management of chemicals in the face of global climate change.
There is an acute need for implantable devices that can report prompt and accurate data about the body’s chemistry. The EU-funded ImplantSens project developed long-term implantable biosensors for glucose monitoring, to improve the management of diabetes. The project also helped train the next generation of scientists to carry on this work.
Around half a million people in Europe rely on a cochlear implant. The EU-funded MOSAICS project is a groundbreaking initiative aimed at enhancing the lives of these patients. The collaborative initiative between researchers and a leading MedTech manufacturer has been instrumental in paving the way for improvements in cochlear implant technology and patient care.
The effectiveness of photodynamic therapy is limited by the lack of oxygen in solid cancers. Now, EU-funded researchers have developed drug delivery nano-carriers to bring oxygen to the tumour site. This strategy could improve the effectiveness of this photodynamic therapy and help to save the lives of citizens affected by cancer.
Cancer and neglected tropical diseases impact millions of people every year. By identifying compounds that specifically target affected cells, EU-funded researchers have opened the door to potential new treatments. These medicines could save lives and benefit citizens both in Europe and around the world.
While researchers were busy developing a handheld device to rapidly detect biomarkers to guide the therapy in lung cancer, the pandemic struck. Realising their device could be adapted to test for coronavirus, researchers refocused their work. The result is the market’s smallest portable PCR device.
