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Genetic engineering

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When the systems that regulate proteins fail, the outcome can be cancer, heart disease or neurodegenerative disorders. Research by the EU-funded Nedd8Activate project offers a window into how the body clears away unwanted proteins. This knowledge could help treat protein dysregulation, and pave the way for drugs that flag disease-causing proteins for elimination.
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The potential for mRNA goes well beyond the COVID-19 vaccine. With the support of the EU-funded MOSaIC project, one research centre in Poland is conducting cutting-edge research in the field, paving the way for new treatments against diseases such as cancer, Alzheimer’s and genetic conditions.
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Ovarian cancer is often diagnosed too late for treatments to work. The EU-funded EARLYDETECT project developed innovative screening tools capable of detecting the disease early. This will help patients receive the therapies they need sooner, before the disease spreads, saving the lives of citizens in the EU and beyond.
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If countries can't train high-quality research staff, they will struggle to deliver innovative cancer treatments. An EU-funded project enabled four academic institutions to exchange staff and share best practices, resulting in various career advancements and successful research grant applications. These will benefit citizens through the researchers' expanding skills to advance cancer treatments.
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Short Bowel Syndrome is a medical disorder without a cure and with limited treatment options. But one EU-funded project aimed to change this by creating a functional small bowel using a patient’s own cells or tissue. The result has the potential to substantially improve the chances of survival and the standard of living for those suffering from the disorder.
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Your father's exercise routine may have made you smarter according to EU-funded researchers studying how lifestyle choices affect brain function and memory. The findings could lead to new treatments for neurodegenerative conditions such as Alzheimer's disease.
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Until recently, there was no treatment specific to alpha-mannosidosis, one of the many rare diseases that jointly affect some 30 million citizens in Europe alone. Today, there is as EU-funded research developed enzyme-replacement therapy to stop the illness in its tracks, and this medicine is on the market.
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Emerging viruses pose a serious threat to global public health. EU-funded research is helping to advance our understanding of how infectious diseases evolve and adapt genetically, informing our efforts to develop an effective response. Researchers have already applied these new methods to several public health crises, including COVID-19.
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EU and industry funded researchers are shedding light on genes that influence the progression of Alzheimer's disease, paving the way for the development of novel drugs and therapeutic strategies that could delay or slow cognitive decline.