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Genetic engineering

A first-ever inside look at how the human body manages proteins

When the systems that regulate proteins fail, the outcome can be cancer, heart disease or neurodegenerative disorders. Research by the EU-funded Nedd8Activate project offers a window into how the body clears away unwanted proteins. This knowledge could help treat protein dysregulation, and pave the way for drugs that flag disease-causing proteins for elimination.

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Twinning boosts excellence in cancer research

If countries can't train high-quality research staff, they will struggle to deliver innovative cancer treatments. An EU-funded project enabled four academic institutions to exchange staff and share best practices, resulting in various career advancements and successful research grant applications. These will benefit citizens through the researchers' expanding skills to advance cancer treatments.

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A revolutionary way of treating Short Bowel Syndrome

Short Bowel Syndrome is a medical disorder without a cure and with limited treatment options. But one EU-funded project aimed to change this by creating a functional small bowel using a patient’s own cells or tissue. The result has the potential to substantially improve the chances of survival and the standard of living for those suffering from the disorder.

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Replacing an enzyme to control a very rare disease

Until recently, there was no treatment specific to alpha-mannosidosis, one of the many rare diseases that jointly affect some 30 million citizens in Europe alone. Today, there is as EU-funded research developed enzyme-replacement therapy to stop the illness in its tracks, and this medicine is on the market.

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Unravelling the mystery of how viruses evolve and spread

Emerging viruses pose a serious threat to global public health. EU-funded research is helping to advance our understanding of how infectious diseases evolve and adapt genetically, informing our efforts to develop an effective response. Researchers have already applied these new methods to several public health crises, including COVID-19.

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