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Europe’s research labs and pharmaceutical companies are both working to discover new drugs, but often speak different dialects. EU-OPENSCREEN was set up to change this by creating a continent-wide research infrastructure for chemical biology and early drug discovery. Within the EU-funded EU-OPENSCREEN-DRIVE project, one of the most effective tools turned out to be not a new machine or invention, but an office with a deceptively simple name: the Industry Liaison Office.
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Extrusion is the process of shaping a raw material by squeezing it through a gap, and is essential for the production of plastic pipes, wire insulation and window frames. But most modern extrusion machines cannot use recycled plastics as a source material. By adapting one single component, the EU-funded NEWEX project allows manufacturers to make high-quality recycled plastic products, keeping waste out of landfill.
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The EU-funded MycoTWIN project took on one of agriculture’s toughest challenges: fungal compounds that contaminate food supplies, especially cereals, nuts and dried fruits. The project brought together researchers from Italy’s National Research Council (CNR-ISPA) and Spain’s University of Valencia (UV) to enhance research capabilities in Türkiye. The result is improved food safety in Europe and beyond.
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When the systems that regulate proteins fail, the outcome can be cancer, heart disease or neurodegenerative disorders. Research by the EU-funded Nedd8Activate project offers a window into how the body clears away unwanted proteins. This knowledge could help treat protein dysregulation, and pave the way for drugs that flag disease-causing proteins for elimination.
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Cancer is one of the leading causes of death in the EU. Researchers in the EU-funded Survive project examined how cells adapt to acidic conditions – a trait that can allow tumours to grow. Their findings highlight new ways to identify aggressive cancers, and point to potential new treatments to regulate acid resistance.
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Science knows no borders. The EU-funded FunGlass project demonstrates how the expertise of top European partners can breathe new life into a young, aspiring institute. An upgrade of the Centre of Excellence for Ceramics, Glass and Silicate Materials in Trenčín, Slovakia, is delivering not only advanced science, but improved economic and social development in the region.
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The steady and debilitating progression of Parkinson’s is thought to be driven by the gradual accumulation of misfolded proteins in the brain. The EU-funded SYN-CHARGE project made the surprising discovery that these problem proteins may be targeted by peptide chains made from mirror image amino acids. The work lays the foundation for potential new therapies for several neurodegenerative diseases.
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Currently there are no therapy options available for those suffering acute radiation sickness. But hope is on the horizon. A combination of carbon and pectin developed by the EU-funded NanoMed project can absorb damaging molecules generated in the body after exposure to radiation. It’s the first step towards a simple pill that can be given to those exposed to high levels of radiation.
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Many of the precursor chemicals essential to our everyday products are derived from fossil fuels. A breakthrough in molecular engineering made by the EU-funded CATACOAT project could help industry transition towards renewable sources of carbon, such as plants. This could help to reduce our carbon footprint, and create new green business opportunities.
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Airborne pollutants are a threat to researchers and citizens alike. Using low-cost sensing technologies, the EU-funded VIDIS project hopes to deliver more accurate assessments of particulate matter exposure. Routine monitoring of air quality could offer significant health benefits for EU citizens.